Questionable content: Fun romantic indy comic. Start at the beginning to make sense. Over 2,000 strips so far so enough reading to keep you busy for a while.
http://questionablecontent.net/
XKCD: A webcomic of romance, sarcasm, math, and language. Be sure to hover over the comic with your cursor for extra insight.
http://xkcd.com/
Saturday Morning Breakfast Cereal: Topical, skeptical and a bit cynical.
http://www.smbc-comics.com/
User Friendly: No longer being produced – go to the first one and start. It’s about a small company and the inevitable conflicts between IT, marketing and management.
http://www.userfriendly.org/